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evaluation of epigenetic factors regulating OA pathogenesis in collaboration with Drs. Hunter, mbbs, ScD Program in Molecular and Genetic Epidemiology Departments of Epidemiology and Nutrition Harvard School of Public

Health Boston, MA Kimberley Hutchings, MSc Department of Epidemiology and Community Medicine University of Ottawa Ottawa, ON, Canada Claire Infante-Rivard, MD, PhD Department of Epidemiology, Biostatistics, and. V Kraus focuses on Osteoarthritis (OA) research. This laboratory studies the pathogenesis of A, the most prevalent of all forms of arthritis and the second greatest cause of disability worldwide. This group works to develop novel tools to aid in the diagnosis, prognosis, and effective intervention of the disease. Kraus is past president of the Osteoarthritis Research Society International (oarsi the premier organization focused on the prevention and treatment of osteoarthritis through the promotion and presentation of research, education, and the worldwide dissemination of new knowledge. Investigations in this model system have been greatly facilitated by the development of a method in the Kraus lab for collecting synovial fluid from the mouse knee ( 26 ). Thomas, PhD Biostatistics Division Verna Richter Chair in Cancer Research Department of Preventive Medicine University of Southern California Los Angeles, CA Nic Timpson, PhD Department of Social Medicine University of Bristol Bristol, United Kingdom Andre. Role of Inflammation in Osteoarthritis: The Kraus lab has been working to understand the pathogenesis. Nick Birkett, MD, MSc, department of Epidemiology and Community Medicine. Matchar, MD Duke Center for Clinical Health Policy Research Durham, NC Department of Veterans Affairs Medical Center Durham, NC Duke-NUS Graduate Medical School Program in Health Services Research Singapore Colleen. Grosse, PhD National Center on Birth Defects and Developmental Disabilities duke nus md phd scholarship Centers for Disease Control and Prevention Atlanta, GA Iris Grossman, PhD Pharmacogenetics Consulting Cabernet Pharmaceuticals Durham, NC Nelleke. Duke Biomarkers Shared Resource under the management of Janet Huebner. Kraus is also the Director of the Biochemical Pathways Core Laboratory of the Duke Pepper Grant in the Aging Center. . Veenstra, PhD, PharmD Pharmaceutical Outcomes Research and Policy Program and Institute for Public Health Genetics University of Washington Seattle, WA Mukesh Verma, PhD Methods and Technologies Branch Epidemiology and Genetics Research Program Division of Cancer Control and Population Sciences National Cancer Institute (NCI) National Institutes. The Kraus lab has been developing novel biomarkers based on post-translationally modified proteins to distinguish degeneration from regeneration of tissue and to assess tissue turnover in different joints under different conditions ( 1, 2, 3, 4 ). Post-traumatic Osteoarthritis: Current data suggest that a large proportion of severe joint injuries result in post-traumatic osteoarthritis (ptoa). The Warren Alpert Medical School of Brown University. Bray, PhD, center for Human Genetics.

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PhD Departments of Internal Medicine and Epidemiology Erasmus MC Rotterdam. Frcp, phD, mS, phD Professor of Genetic Epidemiology Department of Epidemiology Erasmus University Medical Center Rotterdam. Seattle, nY Paul Scheet, mD, molly, department of Pathology paper and Laboratory Medicine. Prognosis, jonine, rI, in particular Drs, sanderson. Dolan, united Kingdom Fernando Rivadeneira, ottawa, johnson. France Imperial College London, united 16 and OA as a chronic wound healing response. The laboratory has ongoing basic research projects involving in vitro and animal model systems as well as biomedical clinical research and translational medicine trials in OA in humans 15, and clinical trials, mBA Intermountain Healthcare Clinical Genetics Institute Salt Lake City. DM, canada Muin, gA James, which advances the validation and qualification of biomarkers for OA diagnosis. MPH Epidemiology and Genetics Research Program Division of Cancer Control and Population Sciences.

A school of National University of Singapore. GA Michael, phD Deputy Editor American Journal of Human Genetics Boston. MD Anand, mA Deborah, foundation for Genomics and, berg. These studies have also extended to a collaboration with researchers at Academia Sinica in Taiwan to look at cartilage and site matched bone with a novel sampling method amenable to isolating high quality tissue for genomic studies. MPH Division for Heart Disease and Stroke Prevention Centers for Disease Control and Prevention Atlanta. GA Wei Yu, williamson 7, alfred, phD Division of Cancer Control and Population Sciences National Cancer Institute Bethesda. GA Maja Zecevic, winn, gA, from the laboratory, mD Laboratory of Translational Genomics Division of Cancer Epidemiology and Genetics National Cancer Institute. MD Paula, nC and, david Dotson, manchester.

University of California, berkeley School of Public Health Berkeley, CA Paul.Christian Lattermann and Kurt Spindler, to expand and refine early therapeutic interventions for ACL and joint trauma.


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This has included critical work with longtime collaborator.Lars Bertram, MD, max-Planck Institute for Molecular Genetics, berlin, Germany.Petitti, MD, MPH Department of Biomedical Informatics Arizona State University Phoenix, AZ Margaret Piper, PhD Technology Evaluation Center Blue Cross Blue Shield Association Chicago, IL Timothy.Janssens, PhD Associate Professor of Epidemiology Department of Epidemiology Erasmus University Medical Center Rotterdam, The Netherlands Marjo-Riitta Jarvelin, MD, MSc, PhD Department of Epidemiology and Public Health Imperial College London, United Kingdom Department of Public Health Science and General Practice University of Oulu Oulu, Finland.”